Thermo Fisher Scientific MRP7 Polyclonal Antibody
Human MRP7 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 세포 해독 및 ABC transporter 연구용에 적합.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRP7 (Product # RP-94747) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644113 |
Product Specific Information
Immunogen sequence:
ILGMLSYTTR LLCTHRTEYL ERADAVLLME AGRLIRAGPP SEILPLVQAV PKAWAENGQE SDSATAQSVQ NPEKTKEGLE EEQSTSGRLL QEESKKE
Highest antigen sequence identity to orthologs:
- Mouse: 71%
- Rat: 72%
Target Information
The MRP family consists of nine similar ABC transporters that function as efflux pumps for structurally diverse lipophilic anions.
MRP7 (Multidrug Resistance-associated Protein 7, ATP-binding cassette sub-family C member 10) is a multi-pass membrane protein of the ABC transporter family.
It mediates ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG) and plays a role in cellular detoxification.
MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains.
Three isoforms are known: Isoform 2 is widely expressed, while Isoform 1 is predominant in the spleen.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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