Thermo Fisher Scientific SNX6 Monoclonal Antibody (335CT6.4.6)
Human SNX6 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot에 1:100~1:500 희석 비율로 사용 가능. Protein G로 정제된 액상 형태로 제공되며, 0.09% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific SNX6 Monoclonal Antibody (335CT6.4.6)
Applications
- Western Blot (WB): Tested dilution 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 335CT6.4.6 |
| Immunogen | SNX6 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C; avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897468 |
Target Information
SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. SNX6 interacts strongly with ActRIIB and moderately with wild-type and kinase-defective mutants of TbetaRII. Among type I receptors, SNX6 interacts only with inactivated TbetaRI. SNXs 1–4 also interact with the transforming growth factor-beta receptor family, showing differing receptor preferences. SNX6 behaves similarly to other SNX proteins in its interactions with receptor tyrosine kinases and forms heteromeric complexes with SNX1, SNX2, SNX4, and SNX6, suggesting oligomeric complex formation in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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