Thermo Fisher Scientific KEAP1 Monoclonal Antibody (297CT6.1.6)
KEAP1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합. Human 시료에 반응하며, 비결합형 액상 형태로 제공. 2 mg/mL 농도, PBS(pH 7.4) 저장 완충액 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 297CT6.1.6 |
| Immunogen | KLH conjugated synthetic peptide between 422–449 amino acids from human KEAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Euglobulin precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897467 |
Target Information
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner, and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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