Thermo Fisher Scientific Phospho-PDE3A (Ser312) Polyclonal Antibody
PDE3A 단백질의 Ser312 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간, 마우스, 랫트 시료에 반응. 고순도 정제 및 안정한 액상 형태로 연구용에 적합.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDE3A (Accession Q14432), corresponding to amino acid residues around phosphorylated Ser312 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817597 |
Product Specific Information
Antibody detects endogenous levels of PDE3A only when phosphorylated at Ser312.
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least five major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-106199_PDE3A_Q14432-1_Rabbit.svg, PA5-106199_PDE3A_Q14432-1_Rabbit_PDP.jpeg)
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