Thermo Fisher Scientific Human IRGC Synthetic Peptide
인간 IRGC 단백질의 아미노 말단 13개 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-20789 항체의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며, PBS 완충액(pH 7.2, 0.1% BSA) 내에 보관됩니다. 연구용으로만 사용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the amino terminus of human IRGC.
PEP-0903 can be used as a blocking peptide with polyclonal antibody PA5-20789.
Target Information
Immunity-related GTPases (IRG), also known as p47 GTPases, are a family of GTPase proteins found in vertebrates that play critical roles in mediating innate resistance to intracellular pathogens.
IRG genes have been identified in mammals and lower species including mice, rats, zebrafish, and humans. Most mouse IRG genes contain interferon-stimulated response elements that mediate transcriptional activation by IFNs.
In humans, only two IRG genes have been found:
- IRGC: Encodes a full-length IRG protein constitutively expressed in testis.
- IRGM: Encodes a truncated protein expressed in cultured cells, including macrophage cell lines.
As human IRGC and IRGM are not controlled by IFN, it is suggested that the host resistance mechanism supported by IRG proteins in mice is lacking in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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