Thermo Fisher Scientific GPR12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

2-4 µg/mL

-

Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human GPR12 / GPCR12. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR12,uniProtId:P47775-1,ncbiNodeId:9606,antigenRange:334,antigenLength:334,antigenImageFileName:PA5-33617_GPR12_P47775-1_Rabbit.svg,antigenImageFileNamePDP:PA5-33617_GPR12_P47775-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550995

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Mouse, Panda, Dog, Pig (94%).

Target Information

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.