Thermo Fisher Scientific GPR109B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

19-38 µg/mL

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Dog, Hamster, Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR109B / HM74.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550984

Product Specific Information

BLAST analysis of the peptide immunogen showed 100% homology with human protein HCAR2 and 50% homology with GPR81.

Percent identity with other species by BLAST analysis: Human, Gorilla, Dog, Hamster, Panda (100%) Mouse, Horse, Guinea pig (95%) Rat (90%).

Target Information

Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.