Thermo Fisher Scientific ARID4A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-2.5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide derived from a region between residues 1119 - 1168 of human Retinoblastoma binding protein 1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARID4A,uniProtId:P29374-1,ncbiNodeId:9606,antigenRange:1119-1168,antigenLength:1257,antigenImageFileName:PA1-32488_ARID4A_P29374-1_Rabbit.svg,antigenImageFileNamePDP:PA1-32488_ARID4A_P29374-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_1956186

Product Specific Information

Recommended positive controls: HepG2.

Predicted reactivity: Cow: 86%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Mouse: 92%; Pig: 86%; Rabbit: 86%; Rat: 93%.

Target Information

ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.