Thermo Fisher Scientific TL1A Polyclonal Antibody
TL1A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, PBS buffer에 0.02% sodium azide가 포함된 액상 형태로 제공됩니다. 4°C 단기, -20°C 장기 보관 권장.
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Applications
- Western Blot (WB): 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to 14 amino acids near the N-terminus of TL1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2206991 |
Product Specific Information
- Recommended positive control: PC-3 Cell Lysate (GTX23954)
Target Information
The TL1A protein is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells but not in B or T cells. Its expression is inducible by TNF and IL-1α. TL1A acts as a ligand for receptors TNFRSF25 and TNFRSF21/DR6, activating NF-κB and MAP kinases. It functions as an autocrine factor inducing apoptosis in endothelial cells and may inhibit angiogenesis. An additional isoform from an alternatively spliced transcript variant has been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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