Thermo Fisher Scientific HTR2B Polyclonal Antibody
HTR2B(5-HT2B) 수용체를 검출하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 1 mg/mL 농도의 액상 형태이며, 연구용으로만 사용됩니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human 5-HT2B receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2119730 |
Product Specific Information
PA1-32494 detects 5-HT2B receptor from human samples.
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformational change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors.
HTR2B also plays a role in perception of pain and regulation of behavior, and is required for normal proliferation of embryonic cardiac myocytes and heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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