Thermo Fisher Scientific IP6K2 Monoclonal Antibody (4F10)
Thermo Fisher Scientific의 IP6K2 단클론 항체(4F10)는 인간 IP6K2 단백질을 인식하는 Mouse IgG2b 형 항체로, Western blot 등 연구용으로 적합합니다. Protein A로 정제된 액상 형태이며 PBS(pH 7.4)에 보존됩니다.
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F10 |
| Immunogen | Full-length recombinant human IP6K2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Inositol hexakisphosphate kinase family members, IP6K1 and IP6K2, have high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. These kinases convert InsP6 to PP-InsP5 and do not exhibit catalytic activity with other inositol pyrophosphates. InsP6 inhibits serine/threonine protein phosphatases and increases calcium influx across the plasma membrane, suggesting a role in insulin exocytosis regulation. IP6K1 and IP6K2 are characterized as approximately 54 kDa and 49 kDa proteins, respectively, and may function as high-energy phosphate donors through ATP synthase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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