Thermo Fisher Scientific RhoG Polyclonal Antibody
RhoG 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성, 고순도 Affinity chromatography 정제, -20°C 보관. 연구용으로 신호전달 및 Ras 관련 단백질 연구에 적합.
- 카탈로그번호
- PA599704
- 판매단위
- pk
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Thermo Fisher Scientific RhoG Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RHOG (Accession P84095), corresponding to amino acid residues Y64–G114 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818637 |
Product Specific Information
Antibody detects endogenous levels of total Rho G.
Target Information
The Ras p21 family of guanine nucleotide proteins plays an important role in signal transduction and is frequently mutated in human cancers. Ras proteins (H-, K-, and N-Ras p21) are part of a larger superfamily, including Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A, and Ral B, which share approximately 50% amino acid homology with Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7, and 8) are about 30% homologous to Ras and are expressed in various cell types. Both Ras p21 and Rho p21 contain a carboxy-terminal CAAX sequence (C: cysteine; A: aliphatic amino acid; X: any amino acid), essential for proper localization and function.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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