Thermo Fisher Scientific RhoBTB3 Polyclonal Antibody
RhoBTB3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 사용 가능. 인간 및 랫트 반응성. 액상 형태로 1 mg/mL 농도, PBS 및 글리세롤 버퍼 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RHOBTB3 (Accession O94955), corresponding to amino acid residues L199–F249 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818638 |
Product Specific Information
Antibody detects endogenous levels of total RHOBTB3.
Target Information
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling, and cell growth.
RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases.
Members of the RhoBTB subfamily are evolutionarily conserved and characterized by a proline-rich region, a GTPase domain, and two tandem BTB repeats.
While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney, and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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