Thermo Fisher Scientific hnRNP A1 Polyclonal Antibody
Thermo Fisher Scientific의 hnRNP A1 Polyclonal Antibody는 인간 hnRNP A1 단백질을 검출하기 위한 고품질 항체로, Western blot, IHC, ICC, IP, RIP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Immunoprecipitation (IP) | 5 µg | - |
| RNA Immunoprecipitation (RIP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from residues 300 to the C-terminus of Human hnRNP A1 (UniProt ID: P09651-1, antigen range: 300–372) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985300 |
Product Specific Information
- Heat-mediated antigen retrieval is recommended prior to tissue staining.
- Predicted to react with mouse, rat, and macaque monkey based on sequence homology.
- Store antibody at 4°C for 1–2 weeks; for long-term storage, keep at -20°C.
Target Information
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These RNA-binding proteins associate with heterogeneous nuclear RNA (hnRNA) and are involved in pre-mRNA processing, mRNA metabolism, and transport. While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. hnRNP A1 contains two quasi-RRM domains that bind RNA and is one of the most abundant core proteins in hnRNP complexes, localized mainly in the nucleoplasm. It is exported from the nucleus bound to mRNA and re-imported after transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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