Thermo Fisher Scientific PSMD2 Monoclonal Antibody (OTI1E7), TrueMAB
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PSMD2 단백질을 인식하는 Mouse monoclonal 항체로 ELISA 및 Luminex 분석에 적합. Human 시료 반응성, Affinity chromatography로 정제, PBS/BSA/glycerol buffer에 보관. -20°C에서 보관하며 동결-해동 반복은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 1:100–1:1,000 |
| Luminex (LUM) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Full length human recombinant PSMD2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- The 20S core consists of four rings (two alpha and two beta subunit rings).
- The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and mediate peptide cleavage in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome variant processes class I MHC peptides.
The PSMD2 gene encodes a non-ATPase subunit of the 19S regulator lid and may also participate in TNF signaling through interaction with the TNF type 1 receptor. A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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