
Thermo Fisher Scientific PSMD2 Monoclonal Antibody (OTI1A12), TrueMAB
Thermo Fisher Scientific의 PSMD2 단일클론 항체(OTI1A12)는 인간 PSMD2 단백질을 인식하는 Mouse IgG1 형 항체로, ELISA 및 Luminex 분석에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용됩니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:100–1:1,000
Luminex (LUM)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A12 |
| Immunogen | Full length human recombinant protein of human PSMD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
The 20S core consists of four rings with 28 subunits (two alpha and two beta rings).
The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal process.
The immunoproteasome variant processes class I MHC peptides.
PSMD2 encodes a non-ATPase subunit of the 19S lid and may participate in the TNF signaling pathway through interaction with TNF receptor type 1.
A pseudogene is located on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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