Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI8G8)
BAIAP2 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성, 비결합형 액상 항체. 고순도 친화 크로마토그래피 정제, 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G8 |
| Immunogen | Full length human recombinant protein of BAIAP2 produced in HEK293 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722889 |
Target Information
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, involved in stress fiber formation and cytokinesis. This protein participates in lamellipodia and filopodia formation in motile cells and may influence neuronal growth-cone guidance. It has been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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