
Thermo Fisher Scientific PDE1B Monoclonal Antibody (OTI6E4)
PDE1B 단백질을 인식하는 Mouse monoclonal 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. Human 시료에 반응하며, Affinity Chromatography로 정제됨. 1 mg/mL 농도의 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E4 |
| Immunogen | Full length human recombinant protein of PDE1B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724965 |
Target Information
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, specifically the PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent phosphodiesterases stimulated by a calcium-calmodulin complex. PDE1B exhibits dual specificity for cAMP and cGMP, with a preference for cGMP as a substrate. These cyclic nucleotides act as key regulators of many physiological processes. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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