Thermo Fisher Scientific Human NOD2 Synthetic Peptide
Human NOD2 단백질의 N-말단 16개 아미노산 서열을 기반으로 한 합성 펩타이드. 폴리클로날 항체 PA5-19991의 차단용으로 사용 가능. 인간 특이적 반응성, 액상 형태, PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 함유. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human NOD2.
PEP-0306 can be used as a blocking peptide with polyclonal antibody PA5-19991.
Target Information
NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs).
NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues).
NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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