Thermo Fisher Scientific Human TLR5 Synthetic Peptide
Human TLR5 중심부 16개 아미노산 서열 기반 합성 펩타이드로, PA5-20185 항체의 블로킹 실험에 사용 가능. 인간 TLR5 단백질 연구용으로 적합하며, 액상 형태로 제공. 정제된 PBS 버퍼에 저장되며 -20°C에서 보관.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human TLR5.
PEP-0315 can be used as a blocking peptide with polyclonal antibody PA5-20185.
Target Information
TLR5 is a Type I membrane protein belonging to the Toll-like receptor family and participates in the innate immune response to microbial agents.
It mediates detection of bacterial flagellins and acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion, and inflammatory response.
TLR5 binds to TIRAP and MyD88 via their respective TIR domains. It is highly expressed in liver, detected in lung, and at very low levels in most other tissues.
The TLR5 gene locus is associated with susceptibility to Salmonella. Mouse strains vary in resistance to S. typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L), and resistant (A, CBA).
The MOLF/Ei strain is highly susceptible, has a unique TLR5 haplotype, and lower TLR5 expression.
A common TLR5 stop codon polymorphism disrupting TLR5 signaling is linked to susceptibility to Legionnaires' disease, highlighting TLR5's role in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Human TLR6 Synthetic Peptide
195,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Human TLR5 Synthetic Peptide
195,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Human TLR5 Synthetic Peptide
195,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Human NALP1 Synthetic Peptide
195,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Human NOD2 Synthetic Peptide
195,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|