Thermo Fisher Scientific EID1 Polyclonal Antibody
EID1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 적합. 인간 시료 반응성, 액상 형태, 1 mg/mL 농도. PBS 및 글리세롤 버퍼로 안정화되어 -20°C에서 보관 가능.
- 카탈로그번호
- PA5115165
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EID1 (Accession Q9Y6B2), corresponding to amino acid residues K72–Y122 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899801 |
Product Specific Information
Antibody detects endogenous levels of total EID1.
Target Information
E1A-like inhibitor of differentiation-1 (EID-1) is an acetyltransferase enzyme that binds both the retinoblastoma protein (Rb) and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein.
EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300 and acetylates histones and non-histone proteins such as NCOA3 co-activator.
By acetylating histones, EID-1 provides a specific tag for transcriptional activation. It also binds phosphorylated CREB protein, mediating cAMP gene regulation and activating transcription of cAMP-responsive genes as a co-activator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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