Thermo Fisher Scientific CD69 Monoclonal Antibody (FN50), PE

Applications

Flow Cytometry (Flow)

• Tested Dilution: 20 µL / 1×10⁶ cells
• View 5 publications

Product Specifications

Additional Formats Available

• Unconjugated
• Alexa Fluor 647
• APC
• FITC
• PerCP
• Request custom conjugation

Product Specific Information

This antibody recognizes an extracellular epitope of CD69, a lymphocyte early activation marker.

Target Information

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide-bonded homodimer with a molecular weight of approximately 60 kDa under non-reducing conditions.
It contains one or two N-linked oligosaccharides and is present on activated platelets.
In normal peripheral blood, a variable percentage of cells express the CD69 antigen, which is involved in lymphocyte signal transduction.
Expression of CD69 is induced upon activation of T lymphocytes and may play a role in proliferation.
Furthermore, the protein may act to transmit signals in natural killer cells and platelets.
Alternative splicing results in multiple transcript variants of CD69.
Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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