Thermo Fisher Scientific CD69 Monoclonal Antibody (FN50), PE
인간 CD69를 인식하는 단클론 항체로, PE 형광 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 림프구 활성화 마커 분석에 사용되며, 565/576 nm의 여기/방출 특성을 가집니다. 4°C에서 암소 보관하며 동결 금지.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 20 µL / 1×10⁶ cells
- View 5 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FN50 |
| Immunogen | anti-µ-stimulated human B lymphocytes |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153579 |
Additional Formats Available
Product Specific Information
This antibody recognizes an extracellular epitope of CD69, a lymphocyte early activation marker.
Target Information
CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide-bonded homodimer with a molecular weight of approximately 60 kDa under non-reducing conditions.
It contains one or two N-linked oligosaccharides and is present on activated platelets.
In normal peripheral blood, a variable percentage of cells express the CD69 antigen, which is involved in lymphocyte signal transduction.
Expression of CD69 is induced upon activation of T lymphocytes and may play a role in proliferation.
Furthermore, the protein may act to transmit signals in natural killer cells and platelets.
Alternative splicing results in multiple transcript variants of CD69.
Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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