Thermo Fisher Scientific CD69 Monoclonal Antibody (FN50)
CD69 단백질을 표적하는 Mouse IgG1 단일클론 항체로 인간 시료에 반응합니다. Flow Cytometry 및 Immunohistochemistry(Frozen)에 적합하며, 다양한 형광 표지 형식으로 제공 가능합니다. 세포 활성화 마커 연구에 활용됩니다.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Assay-Dependent
Flow Cytometry (Flow)
- 1–4 µg/mL
- View 6 publications
Miscellaneous PubMed (Misc)
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FN50 |
| Immunogen | anti-µ-stimulated human B lymphocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154190 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD69, a lymphocyte early activation marker.
Target Information
CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide-bonded homodimer with a molecular weight of approximately 60 kDa under non-reducing conditions. It contains one or two N-linked oligosaccharides and is present on activated platelets. In normal peripheral blood, a variable percentage of cells express CD69, which is involved in lymphocyte signal transduction. Expression of CD69 is induced upon activation of T lymphocytes and may play a role in proliferation. The protein may also transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants. Diseases associated with CD69 dysfunction include coccidioidomycosis and asthma.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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