Thermo Fisher Scientific SH2B3 Monoclonal Antibody (OTI1F6), TrueMAB
인간 SH2B3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. 무보존제, 동결건조 형태이며 재구성 후 1 mg/mL 농도로 사용 가능합니다. 세포 신호전달 및 혈구형성 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F6 |
| Immunogen | Full length human recombinant protein of human SH2B3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SH2B3 encodes a member of the SH2B adaptor protein family involved in various signaling pathways mediated by growth factor and cytokine receptors.
This protein acts as a negative regulator of cytokine signaling and is essential for hematopoiesis.
Mutations in SH2B3 are associated with susceptibility to celiac disease type 13 and insulin-dependent diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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