Thermo Fisher Scientific MVP Monoclonal Antibody (1032)
MVP 단백질을 타겟으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 1032). WB, IHC, Flow, IP 등 다양한 응용에 사용 가능. Human 및 Rat 시료와 반응하며, 단백질 A/G로 정제된 액상 형태로 제공. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
| Flow Cytometry (Flow) | Assay-dependent | – |
| Immunoprecipitation (IP) | 2 µg/mL | – |
| Gel Shift (GS) | 1 mg/mL | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1032 |
| Immunogen | Proteins precipitated with AER317 from the phosphocellulose column flow-through of extract of human breast cancer MCF-7 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10989340 |
Product Specific Information
MA5-13871 targets Major Vault Protein (MVP) in FACS, GS, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples.
The immunogen is proteins precipitated with AER317 from the phosphocellulose column flow-through of extract of human breast cancer MCF-7 cells.
Target Information
This gene encodes the major vault protein, a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport.
This protein mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells.
Overexpression may serve as a useful marker of clinical drug resistance.
This gene produces two transcripts using alternative exon 2 sequences; however, both have identical open reading frames.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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