Thermo Fisher Scientific Bak Polyclonal Antibody
Bak 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·생쥐·햄스터 시료에 반응합니다. IHC(P)에서 2–10 µg/mL로 사용 가능하며, 미토콘드리아 막 위치 단백질 검출에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체입니다.
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Thermo Fisher Scientific Bak Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the internal segment of human Bak |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human pancreatic carcinoma
- Cellular location: Mitochondrion membrane
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to membrane potential loss and cytochrome c release. It also interacts with the tumor suppressor P53 after exposure to cell stress.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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