Thermo Fisher Scientific mGluR4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human mGluR4 (GRM4) for IHC applications. High specificity validated across multiple species. Supplied as unconjugated liquid form, purified by antigen affinity chromatography. Suitable for neuroscience research on ...
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- PA533821
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 19 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Pig, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human GRM4 / MGLUR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551191 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rabbit, Pig (100%)
Rat, Hamster, Dog (94%)
Horse, Opossum (88%)
Target Information
The Metabotropic Glutamate Receptor mGluR4 (GRM4) binds L-glutamate, the major excitatory neurotransmitter in the central nervous system. It activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and may be altered in various neuropathologic conditions.
Metabotropic glutamate receptors are a family of G protein-coupled receptors divided into three groups based on sequence homology, signal transduction mechanisms, and pharmacologic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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