Thermo Fisher Scientific ZC3H8 Monoclonal Antibody (OTI9F11), TrueMAB
인간 ZC3H8 단백질을 인식하는 마우스 단클론 항체로, IHC(P)에서 1:150 희석으로 검증됨. 비결합형, 동결건조 형태로 제공되며 PBS 버퍼에 트레할로스 포함. GATA3 프로모터 억제 및 흉선세포 항상성 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested Dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F11 |
| Immunogen | Full length human recombinant protein of human ZC3H8 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter.
It binds specifically to the 5'-AGGTCTC-3' sequence within the intronic regulatory region (IRR) of the GATA3 gene.
Overexpression induces thymocyte apoptosis, suggesting a role in thymocyte homeostasis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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