Thermo Fisher Scientific hnRNP A1 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal Antibody로 hnRNP A1 단백질 검출에 사용. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 Affinity chromatography 정제, 안정적인 PBS/glycerol buffer 저장. 연구용 전용 제품.
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Thermo Fisher Scientific hnRNP A1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HNRNPA1 (Accession P09651), corresponding to amino acid residues V65–D115 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818369 |
Product Specific Information
Antibody detects endogenous levels of total hnRNP A1.
Target Information
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These RNA-binding proteins form complexes with heterogeneous nuclear RNA (hnRNA) and are involved in pre-mRNA processing, mRNA metabolism, and transport.
While hnRNPs are primarily nuclear, some shuttle between the nucleus and cytoplasm. hnRNP A1 contains two quasi RRM domains that bind RNA and is one of the most abundant core proteins of hnRNP complexes localized in the nucleoplasm. It is exported from the nucleus bound to mRNA and rapidly re-imported.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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