Thermo Fisher Scientific NDUFS1 Polyclonal Antibody
NDUFS1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, Affinity chromatography로 정제됨. PBS와 50% glycerol buffer에 보관되며 -20°C에서 안정적 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NDUFS1 (Accession P28331), corresponding to amino acid residues G115–I165 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900266 |
Product Specific Information
Antibody detects endogenous levels of total NDUFS1.
Target Information
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits and is located at the mitochondrial inner membrane.
This protein exhibits NADH dehydrogenase and oxidoreductase activity, transferring electrons from NADH to the respiratory chain, with ubiquinone as the likely immediate electron acceptor.
As the largest subunit of complex I, it forms part of the iron-sulfur fragment and may contribute to the active site crevice where NADH is oxidized.
Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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