Thermo Fisher Scientific NDUFV3 Polyclonal Antibody
Thermo Fisher Scientific의 NDUFV3 Polyclonal Antibody는 인간 NDUFV3 단백질을 인식하는 토끼 다클론 항체입니다. Western blot에 최적화되어 있으며, 미토콘드리아 복합체 I 연구에 활용됩니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NDUFV3 (Accession P56181), corresponding to amino acid residues V32–Y82 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900269 |
Product Specific Information
Antibody detects endogenous levels of total NDUFV3.
Target Information
Mitochondrial complex I, located in the mitochondrial inner membrane, is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH produced in the Krebs cycle, it transfers electrons to ubiquinone, initiating the electron transport process that leads to the reduction of oxygen to water.
NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also known as NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein that functions as a subunit of complex I, though it is not believed to be directly involved in catalysis.
Defects in complex I subunits can cause various myopathies and neuropathies, making NDUFV3 of significant clinical interest.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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