Thermo Fisher Scientific CD336 (NKp44) Monoclonal Antibody (44.189), PE, eBioscience
인간 CD336(NKp44)을 인식하는 단클론 항체로, PE 형광체가 결합되어 있음. Flow Cytometry에 최적화되어 있으며 5 µL/test로 사용. NK 세포 활성 및 종양 세포 분석 연구에 적합. 4°C 암조건에서 보관, 동결 금지.
- 카탈로그번호
- 12-3369-42
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD336 (NKp44) Monoclonal Antibody (44.189), PE, eBioscience
Thermo Fisher Scientific CD336 (NKp44) Monoclonal Antibody (44.189), PE, eBioscience
Applications and Tested Dilution
- Application: Flow Cytometry
- Tested Dilution: 5 µL (0.125 µg)/test
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Recommended Isotype Control | Mouse IgG2b kappa Isotype Control (eBMG2b), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 44.189 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572607 |
Additional Formats
- APC
- eFluor 450
- Functional Grade
- PerCP-eFluor 710
- Custom conjugation available
Product Specific Information
The monoclonal antibody 44.189 reacts with human CD336 (NKp44/NCR2), a 44-kDa transmembrane glycoprotein of the natural cytotoxicity receptor (NCR) family containing an ITIM domain.
CD336 expression and NK cell activation by this receptor require association with DAP12, an ITAM-containing transmembrane accessory protein.
Originally thought to be expressed only on IL-2-activated NK cells and γδ T lymphocytes, CD336 has since been found on IL-3-stimulated plasmacytoid dendritic cells, αβ T cells in the small intestinal epithelium, and T cells in cord blood.
CD336 is involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
The 44.189 antibody facilitates CD336 crosslinking and is reported for use in flow cytometric analysis.
It has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells.
Use at 5 µL (0.125 µg) per test, where one test corresponds to staining a sample in a final volume of 100 µL.
Cell number can range from 10⁵ to 10⁸ cells/test.
- Excitation: 488–561 nm
- Emission: 578 nm
- Laser Compatibility: Blue, Green, Yellow-Green
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD336 (NKp44/NCR2) is a 44-kDa transmembrane glycoprotein belonging to the NCR family, containing an ITIM domain in the cytoplasmic tail.
Its expression and NK cell activation depend on association with DAP12.
CD336 is expressed in various immune cells and plays a role in innate immune responses against viral infections and tumor proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.