Thermo Fisher Scientific GSTM2 Polyclonal Antibody
Thermo Fisher Scientific GSTM2 Polyclonal Antibody는 인간 GSTM2 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC에 적합하며, 친화 크로마토그래피로 정제된 액상 항체입니다. PBS 버퍼에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human GSTM2 (aa 71–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609072 |
Product Specific Information
- Peptide sequence: TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF
- Sequence homology: Human: 100%; Zebrafish: 79%
Target Information
At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress, by conjugation with glutathione.
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual’s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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