Thermo Fisher Scientific Phospho-PKC zeta (Thr560) Polyclonal Antibody
Phospho-PKC zeta (Thr560) 특이적 폴리클로날 항체로, 인간 및 설치류 등 다양한 종에서 인산화된 PKC zeta 검출에 적합합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도 정제 및 안정적 보관이 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRKCZ (Accession Q05513), corresponding to amino acid residues around phosphorylated Thr560. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816441 |
Product Specific Information
This antibody detects endogenous levels of PKC zeta only when phosphorylated at Threonine 560.
Target Information
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action, response to extracellular signals, and substrate specificity. PKC zeta plays a key regulatory role in various cellular functions, including cell growth and differentiation, gene expression, hormone secretion, and membrane function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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