Thermo Fisher Scientific EBP1 Recombinant Rabbit Monoclonal Antibody (ARC1281)
EBP1 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. HEK293 발현, 비결합형, 액상 형태. 성장 조절 및 리보솜 조립 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1281 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300–394 of human EBP1/PA2G4 (NP_0061822) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849548 |
Product Specific Information
Immunogen sequence:
ELLQPFNVLY EKEGEFVAQF KFTVLLMPNG PMRITSGPFE PDLYKSEMEV QDAELKALLQ SSASRKTQKK KKKKASKTAE NATSGETLEE NEAGD
Target Information
This gene encodes an RNA-binding protein involved in growth regulation. It is present in pre-ribosomal ribonucleoprotein complexes and may play a role in ribosome assembly and rRNA processing. The protein interacts with the cytoplasmic domain of the ErbB3 receptor and contributes to transducing growth regulatory signals. It also acts as a transcriptional co-repressor of androgen receptor-regulated and cell cycle genes through interactions with histone deacetylases. It has been implicated in growth inhibition and differentiation induction of human cancer cells. Six pseudogenes are located on chromosomes 3, 6, 9, 18, 20, and X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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