Thermo Fisher Scientific alpha Galactosidase Recombinant Rabbit Monoclonal Antibody (ARC1213)
Recombinant rabbit monoclonal antibody targeting alpha Galactosidase (GLA). Validated for WB and ELISA. High purity via affinity chromatography. Supplied in PBS buffer with glycerol for stability. Ideal for research use in human, mouse, and rat samples.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1213 |
| Immunogen | Synthetic peptide corresponding to amino acids 50–150 of human Galactosidase alpha (GLA) (UniProt ID: P06280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.23 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849550 |
Product Specific Information
Immunogen sequence:
FMCNLDCQEE PDSCISEKLF MEMAELMVSE GWKDAGYEYL CIDDCWMAPQ RDSEGRLQAD PQRFPHGIRQ LANYVHSKGL KLGIYADVGN KTCAGFPGSF G
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It primarily hydrolyzes ceramide trihexoside and catalyzes the conversion of melibiose into galactose and glucose. Mutations in this gene can disrupt enzyme synthesis and stability, leading to Fabry disease—a rare lysosomal storage disorder resulting from defective catabolism of alpha-D-galactosyl glycolipid moieties.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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