Thermo Fisher Scientific CD267 (TACI) Recombinant Rabbit Monoclonal Antibody (006)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened for optimal production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody specifically recognizes Human TACI/TNFRSF13B/CD267.

Target Information

Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (BLyS/TALL-1/THANK/zTNF4) and APRIL (TALL-2), have been identified.

• BAFF: Induces B cell proliferation and immunoglobulin secretion.
• APRIL: Regulates immunological and non-immunological cell growth.
  Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL.
  TACI and its ligands regulate humoral immune responses, activate NF-κB and c-Jun N-terminal kinase, and are involved in B cell–associated autoimmune diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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