Thermo Fisher Scientific TFPI Recombinant Rabbit Monoclonal Antibody (004)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:250–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the larger rabbit immune repertoire

This antibody has specificity for Mouse TFPI.

Target Information

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor regulating the TF-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in vascular endothelium and plasma, both in free form and complexed with plasma lipoproteins.
The coagulation process begins with formation of a factor VIIa–TF complex, activating proteases (factors IX and X) and leading to fibrin clot formation. TFPI inhibits activated factor X and VIIa–TF proteases in an autoregulatory loop.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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