Thermo Fisher Scientific DUSP12 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DUSP12 (residues 1–50). Validated for WB and IP applications. Supplied unconjugated in liquid form, 1 mg/mL concentration. Recommended storage at 4°C and 1-year shelf life. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 20 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 1 to 50 of human Dual specificity protein phosphatase 12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Dual specificity phosphatases (DUSPs) inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues.
DUSPs are classified into six subgroups based on sequence similarity: PRLs, Cdc14 phosphatases, PTENs, myotubularins, MKPs, and atypical DUSPs.
DUSP inhibitors may modulate MAPK signaling and cellular responses.
DUSP12 (also known as YVH1 or GKAP) contains the consensus DUSP catalytic domain and an extended C-terminal domain possibly involved in glucokinase regulation.
It is localized in the cytoplasm and nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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