Thermo Fisher Scientific PRTN3 Monoclonal Antibody (OTI5B8), TrueMAB
인간 PRTN3 단백질(아미노산 28-248)에 특이적인 마우스 단클론 항체. IHC(P)에서 1:150 희석으로 검증됨. TrueMAB 포맷으로 고순도 정제 및 안정적 액상 형태. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 28–248 of human PRTN3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369).
May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: TA807274_PR3_P24158-1_House_mouse.svg, TA807274_PR3_P24158-1_House_mouse_PDP.jpeg)
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