
Thermo Fisher Scientific FBLIM1 Monoclonal Antibody (OTI3F8), TrueMAB
인간 FBLIM1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합. 액상 형태이며 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보관. 세포 접착 및 형태 조절 관련 연구용으로 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–242 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and multiple C-terminal LIM domains. The protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. It may be involved in assembly and stabilization of actin filaments and plays a role in modulating cell adhesion, morphology, and motility. Additionally, it localizes to the nucleus and may influence cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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