Thermo Fisher Scientific SEMA4D Polyclonal Antibody
Human SEMA4D를 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 4°C 보관. CD100/Semaphorin 4D 관련 연구용으로 적합.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 800–850 of Human Semaphorin 4D (CD100), including Somain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM), and Short Cytoplasmic Domain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development.
CD100 (Semaphorin 4D), a 150 kDa homodimer, induces B cell aggregation and enhances viability in vitro.
It modulates CD40–CD40L signaling by promoting B cell survival and reducing CD23 expression.
CD72 acts as a lymphocyte receptor for CD100, regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells, weakly on NK cells, EBV-transformed B cells, monocytes, and tumor/peripheral blood T cell lines, and at higher density on activated T and B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: A304-394A_CD100_SEMA4D_Q92854-1_Rabbit.svg, A304-394A_CD100_SEMA4D_Q92854-1_Rabbit_PDP.jpeg)
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