Thermo Fisher Scientific CD19 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD19, suitable for Western blot and immunoprecipitation. Recognizes residues 506–556 of CD19. Supplied as liquid, unconjugated, 1 mg/mL concentration. For research use only.
- 카탈로그번호
- A304392Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD19 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 506 to 556 of human CD19 molecule |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also be present on myeloid leukemia cells, particularly of monocytic lineage. CD19 serves as a key functional regulator of normal and malignant B cell proliferation and is expressed in all B cell precursor leukemias. It acts as a signal-amplifying coreceptor for the B cell receptor (BCR), lowering the threshold for antigen receptor-dependent stimulation. CD19 can also signal independently of BCR co-ligation and functions as a central regulatory component for multiple signaling pathways. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression causes B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.