
Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Recombinant Rabbit Monoclonal Antibody (NGFR, 2550R)
NGFR(p75)/CD271 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot 및 IHC(파라핀 절편)에서 검증됨. HEK293 세포 발현, Protein A/G 정제, 4°C 보관. 신경세포 발달 및 손상 연구용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NGFR, 2550R |
| Immunogen | Recombinant human p75 NGFR protein fragment (around aa 281–421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both the peripheral and central nervous systems, as well as other neural crest-derived cell types.
Developing sympathetic neurons are dependent upon nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are useful in detecting and characterizing NGFR p75, contributing to the study of neuronal development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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