Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Recombinant Rabbit Monoclonal Antibody (NGFR, 2550R)
NGFR(p75)/CD271에 특이적인 재조합 토끼 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 시료 반응성이 있으며, Protein A/G로 정제된 액상 항체입니다. 신경세포 생존 및 분화 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NGFR, 2550R |
| Immunogen | Recombinant human p75 NGFR protein fragment (around aa 281–421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons are dependent on nerve growth factor (NGF) during the target competition period in vivo.
Antibodies specific to NGFR p75 are valuable for detecting and characterizing NGFR p75, aiding in the study of neural development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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