Thermo Fisher Scientific HNRNPL Monoclonal Antibody (OTI9G7), TrueMAB
Human HNRNPL 단백질(aa 270-502)에 특이적인 Mouse IgG1 단일클론 항체. Western blot 및 IHC(P) 검증 완료. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose) 보존. 연구용으로 mRNA 처리 및 hnRNP 복합체 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 270–502 of human HNRNPL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments with this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, form complexes with specific proteins known as heterogeneous nuclear ribonucleoproteins (hnRNPs).
HNRNPL is one of the proteins stably associated with hnRNP complexes and plays a key role in mRNA formation, packaging, processing, and function.
It is found in the nucleoplasm as part of the hnRNP complex and can also exist outside the nucleus. hnRNP proteins shuttle between the nucleus and cytoplasm, suggesting potential cytoplasmic functions.
Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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