Thermo Fisher Scientific HTRA2 Recombinant Rabbit Monoclonal Antibody (ARC0864)
HTRA2 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 높은 특이성과 재현성을 제공합니다. 인간, 생쥐, 랫드 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0864 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100–200 of human HTRA2 (O43464) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849318 |
Product Specific Information
Immunogen sequence:
GTRSRAWLAV ALGAGGAVLL LLWGGGRGPP AVLAAVPSPP PASPRSQYNF IADVVEKTAP AVVYIEILDR HPFLGREVPI SNGSGFVVAA DGLIVTNAHV V
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. A serine protease, Omi/HtrA2, is released from mitochondria upon induction of apoptosis and binds to IAP. Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. Deregulated expression of Omi in the cytoplasm induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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