Thermo Fisher Scientific Phospho-CD61 (Tyr785) Polyclonal Antibody
Phospho-CD61 (Tyr785) 폴리클로날 항체로 인테그린 베타3의 Tyr785 인산화 형태를 특이적으로 검출. WB 및 ICC/IF에 적합하며 사람, 생쥐, 랫트 반응. 고순도 정제, PBS/glycerol buffer, -20°C 저장.
- 카탈로그번호
- PA599351
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human ITGB3 (Accession P05106), corresponding to amino acid residues around phosphorylated Tyr785 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818284 |
Product Specific Information
Antibody detects endogenous levels of Integrin beta3 only when phosphorylated at Tyrosine 785.
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein expressed on megakaryocytes, platelets, and their precursors. It functions in platelet aggregation and serves as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin.
CD61 (105 kDa) associates with alpha IIb integrin (CD41) or alpha V integrin (CD51). It plays roles in cell adhesion and signaling.
Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-99351_CD61_Integrin_beta_3_P05106-1_Rabbit.svg, PA5-99351_CD61_Integrin_beta_3_P05106-1_Rabbit_PDP.jpeg)
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