Thermo Fisher Scientific UHRF1 Polyclonal Antibody
Thermo Fisher Scientific의 UHRF1 Polyclonal Antibody는 마우스 및 랫트 반응성을 가지며, Western blot과 IHC에 사용 가능합니다. 합성 펩타이드 항원으로 제작된 Rabbit Ig 폴리클로날 항체로, 연구용으로 적합하며 안정적인 장기 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 2–50 of mouse UHRF1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: UHRF1.
Target Information
UHRF1 encodes a member of the RING-finger type E3 ubiquitin ligase subfamily. This protein binds to specific DNA sequences and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues through G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIα and retinoblastoma gene expression and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: OSU00017W-100UL_UHRF1_Q8VDF2-1_Rabbit.svg, OSU00017W-100UL_UHRF1_Q8VDF2-1_Rabbit_PDP.jpeg)
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