Thermo Fisher Scientific CaMKII beta/gamma/delta Polyclonal Antibody
CaMKII beta/gamma/delta 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 IHC(P) 적용 가능. 고순도(>95%) 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도. 연구용으로 Ca2+/calmodulin 의존성 단백질 인산화 연구에 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 248–299 of human CaMKII beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553587 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 50–80 kDa.
Purity is >95% by SDS-PAGE.
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII, and CaMKIV.
CaMKII is an ubiquitously expressed serine/threonine protein kinase activated by Ca²⁺ and calmodulin (CaM), involved in regulation of the cell cycle and transcription.
There are four CaMKII isozymes — alpha, beta, gamma, and delta — which may or may not be coexpressed in the same tissue type.
CaMKIV is stimulated by Ca²⁺ and CaM but also requires phosphorylation by a CaMK for full activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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